Hannah regularly meets with her sisters Holly and Lee to discuss the weeks' events. It's what they don't always tell each other that forms the film's various subplots. Hannah is married to rock-star manager Elliot, who carries a torch for Lee, who in turn lives with pompous Soho artist Frederick. Meanwhile, Holly, a neurotic actress and eternal loser in love, dates TV producer Mickey, who used to be married to Hannah and spends most of the film convinced that he's about to die.